Small Business Opportunities

NCRR participates in two federal grant programs that provide funding to small businesses—the Small Business Innovation Research (SBIR) program and the Small Business Technology Transfer (STTR) program.

Both programs seek to increase the participation of small businesses in federally supported research and development (R&D) and to increase private sector commercialization of technology developed through federally supported R&D.

Grant Programs

• (R43-R44) Small Business Innovation Research (SBIR) grants support domestic small business concerns to engage in research/research and development that has the potential for commercialization. Phase I, which uses the R43 funding mechanism, is normally for six months for an amount up to $100,000. Phase II, which uses the R44 funding mechanism, is for two years and for up to $750,000. Receipt deadlines for applications are April 5, August 5, and December 5 of each year.
• (R41-R42) Small Business Technology Transfer (STTR) grants support innovative research in the United States that results in commercial products or services that benefit the public. An STTR grant requires research partners at universities and other non-profit research institutions to have a formal collaborative relationship with the small business concern. At least 40 percent of the STTR research project is to be conducted by the small business concern and at least 30 percent of the work is to be conducted by the single, "partnering" research institution. Phase I, which uses the R41 funding mechanism, is for one year for an amount up to $100,000. Normally Phase II, which uses the R42 mechanism, is for two years and for up to $500,000. This total includes direct costs, indirect costs, and fixed fees. If justified, applicants may propose longer periods of time and greater amounts of funds. Receipt deadlines for applications are April 5, August 5, and December 5 of each year.

There are significant differences between the two programs. For detailed program information, refer to the NIH Small Business Opportunities Web site.

Funding Areas

Typically, NCRR requests applications for grants, but it may solicit contract proposals as well. Each NCRR division provides funding in areas that complement its core programs.

Biomedical Technology

The Division of Biomedical Technology is especially interested in funding technology driven research on new or improved instruments, devices, and related methodologies that may have broad application to biomedical research. READ MORE >>

Clinical Research

The Division for Clinical Research Resources is especially interested in the application of clinical technology, instruments, devices and related methodologies that may have broad application to clinical research, especially as it pertains to enhancing the ability to do clinical research. READ MORE >>

Comparative Medicine

The Division of Comparative Medicine is especially interested in funding research to develop biomedical methods and technologies that relate to improvements in laboratory animal care, use, and management. READ MORE >>

Research Infrastructure

The Division of Research Infrasructure is especially interested in funding the development of discovery-oriented software for education on health science topics that targets K-12 and undergraduate students. READ MORE >>