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The CTSA Evaluation Steering Committee provides a forum for institutions to exchange information about their evaluation approaches, challenges, and progress. This committee also coordinates institutional evaluation efforts with the plans for the National CTSA Consortium Evaluation. This committee has had five meetings, three Web-based meetings and two face-to-face meetings. The two face-to-face meetings were held in Maryland on January 29, 2007, and February 8, 2008. Dr. Harold Pincus (Columbia) chairs this steering committee.
The Evaluation Steering Committee recently created three workgroups to address some of the most pressing concerns.
Defining the Terms of EvaluationThe Definitions and Measurement Workgroup will identify, prioritize, and analyze definitional constructs that have significant relevance across CTSAs, such as translational research, disciplinarity, and collaboration, among others. Over time, the workgroup expects to synthesize and disseminate sound measurement tools, approaches, and concepts. (Chair: Dr. Bill Trochim, Cornell)
Sharing ResourcesThe goal of this workgroup is to cultivate a community of committed individuals willing to share their instruments and processes. As a launching point, the workgroup will encourage Consortium members to post requests or share resources on the CTSA Wiki on such topics as needs assessment, user satisfaction, culture change, training, etc. (Chair: Dr. Jodi Segal, Johns Hopkins)
Evaluating Connections Among Consortium MembersThe Social Network Analysis (SNA) Workgroup explores SNA as a tool to assess communication and collaboration across CTSA sites. SNA can visually depict the perceived strength of relationships among individual groups, identifying strong and weak connections among them. SNA can show changes over time in relationships, which in turn can demonstrate how the CTSA program is affecting the way individuals or groups are working with each other. (Chair: Dr. Julie Rainwater, UC Davis)
During the February 2008 meeting, an additional workgroup was formed:
IRB Issues and EvaluationThis workgroup will consider possibilities to harmonize IRB evaluation issues across institutions, explore discussions with other CTSA Steering Committees (e.g., alternate IRB Models, Regulatory, Clinical Research Ethics), and identify ways to achieve greater transparency. The group will work on developing a set of tools to educate IRBs about evaluation and provide examples of key features that an IRB would review for exemption. (Chair: Dr. Paul Moberg, Wisconsin)
Also, during the February 2008 meeting, Dr. Doris Rubio (Pittsburgh) facilitated round robin discussions about the role of the evaluator and how it varies across the institutions with participants sharing their approaches and challenges. Dr. Ann Dozier (Rochester) led a series of discussions about how to capture the broader effect a CTSA may have in terms of economic impact and culture change, to name a few. These topics generated a lot of discussion and will continue to be explored at future meetings.
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| West Coast Grantees Join Forces to Advance Clinical and Translational Science |
Provided by: Chris Kelleher, Oregon Clinical and Translational Research Institute
Fifty-six representatives from four CTSA grantee institutions met on February 4 in Portland, Oregon, for the first meeting of what they call the “West Coast Consortium.”
The meeting initially was intended to develop a partnership between grantees at the University of California, Davis, and Oregon Health & Science University. However, as planning for the event got under way, the advantages of a larger discussion became readily apparent, and both the University of California, San Francisco, and the University of Washington began contributing to a more ambitious agenda.
In addition to the natural bond of shared geography, each group recognized similarities—as well as intriguing differences—in both mission and structure. All were eager to explore opportunities for sharing experiences, building connections to other NCRR-supported programs (such as the National Primate Research Centers), and pooling resources to strengthen each other’s programs. There was hope, moreover, that this effort could serve as a model for consortium-building at the national level.
To ensure the most efficient use of time during the meeting, program representatives held advance planning calls with their counterparts at the other universities to identify synergistic areas of focus. Partner institutions, including Kaiser Permanente and Group Health Cooperative, also helped organize and facilitate the meeting and were well represented among the participants.
The meeting began with presentations from university representatives focusing on programmatic strengths and anticipated opportunities for collaboration. Next came a facilitated discussion that examined a meta-level question relevant to all participants—“How do we build and support investigator collaborations within our CTSAs?”—with the intention of cross-pollinating between programs and disciplines, as well as between institutions. Lunchtime break-out sessions provided further opportunities for potential partnership. The fruits of those discussions were shared in the afternoon, with concentration on key areas and a sharing of thoughts about how best to build the consortium.
Several efforts are now under way to advance this new West Coast consortium. For example, members are considering a plan to contribute a portion of their NCRR pilot funding toward the support of CTSA grantee collaborations. The biomedical informatics teams at UC Davis and Oregon now hold monthly conference calls to develop best practices and synchronize priorities, and the education groups at those institutions have arranged both for reciprocal review of K12 scholar award applications and for shared identification of core competencies. Meanwhile, planning has begun for another gathering of the four institutions in June. The meeting will be scheduled to coordinate with planned regional community workshops and likely will focus on sharing best practices in the areas of education, informatics, and translation.
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| Timeline for Identifying the 2008 CTSA Awardees |
The CTSA applications received on November 7, 2007, in response to RFA-RM-07-007 were reviewed in February, 2008. The priority scores from the reviews of the CTSA applications have been posted to the NIH Commons, and Summary statements will be available in the first weeks of April. Due to the complexity of the budget process for the CTSA program, NCRR will begin in March to request “just in time” information for revised budgets from applicants who are likely to be funded as well as from those who are in a “grey zone,” where the potential for funding is uncertain.
The NCRR Advisory Council will meet on May 14 to make second-level review recommendations. On May 15, NCRR will notify the institutions that will receive CTSA grants; the public announcement will follow in July when the Notice of Grant Awards are issued.
The number of awards to be made will depend on recommendations by reviewers, the funds available, and the Council review of the funding plan.
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| Institutional CTSA Events |
University of Pennsylvania Symposium
The third international ITMAT Symposium will be held on April 14–15, 2008. This year’s title is Academia in Drug Discovery and Development.
For more information, please visit: http://www.itmat.upenn.edu/symposium.shtml.
University of Pennsylvania Annual Conference on Statistical Issues in Clinical Trials: From Bench to Bedside to Community
The topic of the April 18, 2008, conference is Early, Translational and Proof-of-Concept Studies: The “Go/No Go” Decisions.
For more information, please visit: http://www.cceb.upenn.edu/biostat/conferences/ClinTrials08/.
Please note: We recognize that this is not a complete listing of institutional CTSA events with open attendance. Please send your CTSA-sponsored institutional event to Kameha Kidd, kiddka@mail.nih.gov, for inclusion in newsletters and on the CTSAweb.org Events page.
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CTSA Pre-submission Videocast—March 7, 2008, 2:00–4:00 p.m. ET
NCRR and other NIH staff explain the goals and objectives of the CTSA program and answer questions. View the CTSA Pre-submission Videocast (requires free RealPlayer). |
CTSA Solicitation
The National Center for Research Resources, through a contract provided by Booz Allen Hamilton, issued a Request for Proposals, RFP 08-001, for Clinical and Translational Information Exchange Environment Pilot Projects on February 4, 2008. Responses are due April 14, 2008. Click to learn more.
| Upcoming Committee Meeting Dates |
Key: CTSA
Consortium Meeting
CTSA
Consortium Workshop NIH
Staff Meeting |
| Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
3
| NIH Staff Meeting |
Pediatrics
3:30–5:00 p.m.
Rockledge II, Room 10091 |
| CTSA Consortium Meeting |
Informatics
User Needs Interest Group
10:00–11:00 a.m.
Call: 1-866-285-7778
Access Code: 4636762
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| NIH Staff Meeting |
Resource Access Subgroup
10:00–10:45 a.m.
NCRR Conference Room 1037
Web Participation
Call: 1-866-519-2804
Access Code: 704005
NIH coordinator
Rosmarie Filart |
| CTSA Consortium Meeting |
Regulatory and Ethics IRB Taskforce
11:00 a.m.–12:00 p.m.
Call: 1-866-285-7778
Access Code: 2739273
NIH coordinator
Daniel Rosenblum |
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4
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5 |
6 |
7
| CTSA Consortium Meeting |
Informatics
Directors and Project Group Leads
1:00–2:00 p.m.
Call: 1-866-285-7778
Access Code: 4636762 |
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10
| CTSA Consortium Meeting |
Clinical Research Ethics
2:00–4:00 p.m.
Call: 1-866-285-7778
Access Code: 2739273
NIH coordinators
Christine Grady
Daniel Rosenblum |
| CTSA Consortium Meeting |
Informatics User Needs Interest Group
10:00–11:00 a.m.
Call: 1-866-285-7778
Access Code: 4636762 |
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11 |
12
| NIH Staff Meeting |
Translational
3:30–4:30 p.m.
Democracy 1, 9th Floor, Conference
Call: 1-866-285-7778
Access Code: 8726752 |
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13
| CTSA Consortium Meeting |
Community Engagement Community-Based Academic and Practice Partnership Workgroup
12:00–1:00 p.m.
Call: 1-866-285-7778
Access Code: 2666864 |
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14
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17
| CTSA Consortium Meeting |
Education/Career Development Operations Committee
1:00–2:00 p.m.
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| CTSA Consortium Meeting |
Informatics
User Needs Interest Group
10:00–11:00 a.m.
Call: 1-866-285-7778
Access Code: 4636762
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18
| CTSA Consortium Meeting |
Public Private Partnerships Aggregating Resources Workgroup
3:30–5:00 p.m.
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19
| CTSA Consortium Meeting |
Public Private Partnerships Agreements Workgroup
3:30–5:00 p.m.
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20
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21
| CTSA Consortium Meeting |
Community Engagement Operations Committee
12:00–1:00 p.m.
Call: 1-866-285-7778
Access Code: 266864 |
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24
| CTSA Consortium Meeting |
Informatics
User Needs Interest Group
10:00–11:00 a.m.
Call: 1-866-285-7778
Access Code: 4636762
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25
| CTSA Consortium Meeting |
Administration Grants Management Taskforce
1:00–2:00 p.m.
Call: 1-866-285-7778
Access Code: 2364694
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| CTSA Consortium Meeting |
Biostatistics/ Epidemiology/Research Design Evaluation Task Force
4:00–5:00 p.m.
Call: 1-866-285-7778
Access Code: 2467828 |
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26
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27
| CTSA Consortium Meeting |
Communications Communication Systems and Information Management Taskforce
3:00–4:00 p.m.
Call: 1-866-285-7778
Access Code: 6864228 |
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28
| CTSA Consortium Meeting |
Regulatory Knowledge
2:00–3:00 p.m.
Democracy 1, Room 1037
Web Participation
Call: 1-866-244-8528
Access Code: 946313
NIH coordinator
Jody Sachs |
| CTSA Consortium Meeting |
Informatics
Operations Committee
12:00–1:00 p.m.
Call: 1-866-285-7778
Access Code: 4636762
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31
| CTSA Consortium Meeting |
Informatics
User Needs Interest Group
10:00–11:00 a.m.
Call: 1-866-285-7778
Access Code: 4636762 |
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1
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2
| CTSA Consortium Meeting |
Communications Operations Committee
11:00 a.m.–12:00 p.m.
Call: 1-866-285-7778
Access Code: 6864228
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| 3
| CTSA Consortium Meeting |
Translational
2:00–3:00 p.m.
Bethesda, Democracy 1, Conference Room 987
Web Participation
Call: 1-866-519-2804
Access Code: 704005
NIH coordinator
Doug Sheeley
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| 4
| CTSA Consortium Meeting |
Informatics
Directors and Project Group Leads
1:00–2:00 p.m.
Call: 1-866-285-7778
Access Code: 4636762 |
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| * Please note that the meetings and events listed in this newsletter are provided for your information. If you wish to participate, please contact the NIH coordinator. |
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