March 3, 2008
Featured CTSA Committee

West Coast Grantees Join Forces to Advance Clinical and Translational Science

Timeline for Identifying the 2008 CTSA Awardees

Institutional CTSA Events

Announcements

Upcoming Committee Meeting Dates

Updated Information on CTSAweb.org

Featured CTSA Committee


The CTSA Evaluation Steering Committee provides a forum for institutions to exchange information about their evaluation approaches, challenges, and progress. This committee also coordinates institutional evaluation efforts with the plans for the National CTSA Consortium Evaluation. This committee has had five meetings, three Web-based meetings and two face-to-face meetings. The two face-to-face meetings were held in Maryland on January 29, 2007, and February 8, 2008. Dr. Harold Pincus (Columbia) chairs this steering committee.

The Evaluation Steering Committee recently created three workgroups to address some of the most pressing concerns.

Defining the Terms of Evaluation—The Definitions and Measurement Workgroup will identify, prioritize, and analyze definitional constructs that have significant relevance across CTSAs, such as translational research, disciplinarity, and collaboration, among others. Over time, the workgroup expects to synthesize and disseminate sound measurement tools, approaches, and concepts. (Chair: Dr. Bill Trochim, Cornell)

Sharing Resources—The goal of this workgroup is to cultivate a community of committed individuals willing to share their instruments and processes. As a launching point, the workgroup will encourage Consortium members to post requests or share resources on the CTSA Wiki on such topics as needs assessment, user satisfaction, culture change, training, etc. (Chair: Dr. Jodi Segal, Johns Hopkins)

Evaluating Connections Among Consortium Members—The Social Network Analysis (SNA) Workgroup explores SNA as a tool to assess communication and collaboration across CTSA sites. SNA can visually depict the perceived strength of relationships among individual groups, identifying strong and weak connections among them. SNA can show changes over time in relationships, which in turn can demonstrate how the CTSA program is affecting the way individuals or groups are working with each other. (Chair: Dr. Julie Rainwater, UC Davis)

During the February 2008 meeting, an additional workgroup was formed:

IRB Issues and Evaluation—This workgroup will consider possibilities to harmonize IRB evaluation issues across institutions, explore discussions with other CTSA Steering Committees (e.g., alternate IRB Models, Regulatory, Clinical Research Ethics), and identify ways to achieve greater transparency. The group will work on developing a set of tools to educate IRBs about evaluation and provide examples of key features that an IRB would review for exemption. (Chair: Dr. Paul Moberg, Wisconsin)

Also, during the February 2008 meeting, Dr. Doris Rubio (Pittsburgh) facilitated round robin discussions about the role of the evaluator and how it varies across the institutions with participants sharing their approaches and challenges. Dr. Ann Dozier (Rochester) led a series of discussions about how to capture the broader effect a CTSA may have in terms of economic impact and culture change, to name a few. These topics generated a lot of discussion and will continue to be explored at future meetings.


West Coast Grantees Join Forces to Advance Clinical and Translational Science


Provided by: Chris Kelleher, Oregon Clinical and Translational Research Institute

Fifty-six representatives from four CTSA grantee institutions met on February 4 in Portland, Oregon, for the first meeting of what they call the “West Coast Consortium.”

The meeting initially was intended to develop a partnership between grantees at the University of California, Davis, and Oregon Health & Science University. However, as planning for the event got under way, the advantages of a larger discussion became readily apparent, and both the University of California, San Francisco, and the University of Washington began contributing to a more ambitious agenda.

In addition to the natural bond of shared geography, each group recognized similarities—as well as intriguing differences—in both mission and structure. All were eager to explore opportunities for sharing experiences, building connections to other NCRR-supported programs (such as the National Primate Research Centers), and pooling resources to strengthen each other’s programs. There was hope, moreover, that this effort could serve as a model for consortium-building at the national level.

To ensure the most efficient use of time during the meeting, program representatives held advance planning calls with their counterparts at the other universities to identify synergistic areas of focus. Partner institutions, including Kaiser Permanente and Group Health Cooperative, also helped organize and facilitate the meeting and were well represented among the participants.

The meeting began with presentations from university representatives focusing on programmatic strengths and anticipated opportunities for collaboration. Next came a facilitated discussion that examined a meta-level question relevant to all participants—“How do we build and support investigator collaborations within our CTSAs?”—with the intention of cross-pollinating between programs and disciplines, as well as between institutions. Lunchtime break-out sessions provided further opportunities for potential partnership. The fruits of those discussions were shared in the afternoon, with concentration on key areas and a sharing of thoughts about how best to build the consortium.

Several efforts are now under way to advance this new West Coast consortium. For example, members are considering a plan to contribute a portion of their NCRR pilot funding toward the support of CTSA grantee collaborations. The biomedical informatics teams at UC Davis and Oregon now hold monthly conference calls to develop best practices and synchronize priorities, and the education groups at those institutions have arranged both for reciprocal review of K12 scholar award applications and for shared identification of core competencies. Meanwhile, planning has begun for another gathering of the four institutions in June. The meeting will be scheduled to coordinate with planned regional community workshops and likely will focus on sharing best practices in the areas of education, informatics, and translation.


Timeline for Identifying the 2008 CTSA Awardees

The CTSA applications received on November 7, 2007, in response to RFA-RM-07-007 were reviewed in February, 2008. The priority scores from the reviews of the CTSA applications have been posted to the NIH Commons, and Summary statements will be available in the first weeks of April. Due to the complexity of the budget process for the CTSA program, NCRR will begin in March to request “just in time” information for revised budgets from applicants who are likely to be funded as well as from those who are in a “grey zone,” where the potential for funding is uncertain.

The NCRR Advisory Council will meet on May 14 to make second-level review recommendations. On May 15, NCRR will notify the institutions that will receive CTSA grants; the public announcement will follow in July when the Notice of Grant Awards are issued.

The number of awards to be made will depend on recommendations by reviewers, the funds available, and the Council review of the funding plan.



Institutional CTSA Events

University of Pennsylvania Symposium

The third international ITMAT Symposium will be held on April 14–15, 2008. This year’s title is Academia in Drug Discovery and Development.
For more information, please visit: http://www.itmat.upenn.edu/symposium.shtml.


University of Pennsylvania Annual Conference on Statistical Issues in Clinical Trials: From Bench to Bedside to Community

The topic of the April 18, 2008, conference is Early, Translational and Proof-of-Concept Studies: The “Go/No Go” Decisions.
For more information, please visit: http://www.cceb.upenn.edu/biostat/conferences/ClinTrials08/.


Please note: We recognize that this is not a complete listing of institutional CTSA events with open attendance. Please send your CTSA-sponsored institutional event to Kameha Kidd, kiddka@mail.nih.gov, for inclusion in newsletters and on the CTSAweb.org Events page.


Announcements

CTSA Pre-submission Videocast—March 7, 2008, 2:00–4:00 p.m. ET

NCRR and other NIH staff explain the goals and objectives of the CTSA program and answer questions. View the CTSA Pre-submission Videocast (requires free RealPlayer).



CTSA Solicitation

The National Center for Research Resources, through a contract provided by Booz Allen Hamilton, issued a Request for Proposals, RFP 08-001, for Clinical and Translational Information Exchange Environment Pilot Projects on February 4, 2008. Responses are due April 14, 2008. Click to learn more.

Upcoming Committee Meeting Dates

Key: CTSA Consortium Meeting   CTSA Consortium Workshop NIH Staff Meeting
March 2008
Monday
Tuesday
Wednesday
Thursday
Friday

 3

NIH Staff Meeting
Pediatrics
3:30–5:00 p.m.

Rockledge II, Room 10091

CTSA Consortium Meeting
Informatics
User Needs Interest Group
10:00–11:00 a.m.
Call: 1-866-285-7778
Access Code: 4636762


NIH Staff Meeting

Resource Access Subgroup
10:00–10:45 a.m.
NCRR Conference Room 1037
Web Participation

Call: 1-866-519-2804
Access Code: 704005

NIH coordinator
Rosmarie Filart


CTSA Consortium Meeting
Regulatory and Ethics IRB Taskforce
11:00 a.m.–12:00 p.m.
Call: 1-866-285-7778
Access Code: 2739273

NIH coordinator
Daniel Rosenblum

 4

CTSA Consortium Meeting
Administration Workgroup
1:00–2:00 p.m.
Call: 1-866-285-7778
Access Code: 2364694

NIH coordinators
Elaine Collier
Kameha Kidd
Iris Obrams

 

 5

 6

 7

CTSA Consortium Meeting
Informatics Directors and Project Group Leads
1:00–2:00 p.m.
Call: 1-866-285-7778
Access Code: 4636762

 

 10

CTSA Consortium Meeting
Clinical Research Ethics
2:00–4:00 p.m.
Call: 1-866-285-7778
Access Code: 2739273

NIH coordinators
Christine Grady
Daniel Rosenblum

CTSA Consortium Meeting
Informatics User Needs Interest Group
10:00–11:00 a.m.
Call: 1-866-285-7778
Access Code: 4636762

 11

 12

NIH Staff Meeting

Translational
3:30–4:30 p.m.

Democracy 1, 9th Floor, Conference
Call: 1-866-285-7778
Access Code: 8726752

 

 13

CTSA Consortium Meeting
Community Engagement Community-Based Academic and Practice Partnership Workgroup
12:00–1:00 p.m.
Call: 1-866-285-7778
Access Code: 2666864

 

 14

 

 17

CTSA Consortium Meeting
Education/Career Development Operations Committee
1:00–2:00 p.m.


CTSA Consortium Meeting
Informatics
User Needs Interest Group
10:00–11:00 a.m.
Call: 1-866-285-7778
Access Code: 4636762

 18

CTSA Consortium Meeting
CTSA Consortium Oversight
1:00–2:00 p.m.
Web Participation
Call: 1-800-256-1922
Access Code: 447142

NIH coordinator
Anthony Hayward

CTSA Consortium Meeting
Public Private Partnerships Aggregating Resources Workgroup
3:30–5:00 p.m.

 19

CTSA Consortium Meeting

Communications
2:00–4:00 p.m.
Bethesda, Democracy 1, Room 987
Web Participation

Call: 1-877-239-6423
Access Code: 344907

NIH coordinators
Kameha Kidd
Lori Mulligan


CTSA Consortium Meeting
Public Private Partnerships Agreements Workgroup
3:30–5:00 p.m.

 20

 

 21

CTSA Consortium Meeting
Community Engagement Operations Committee
12:00–1:00 p.m.
Call: 1-866-285-7778
Access Code: 266864

 24

CTSA Consortium Meeting
Informatics
User Needs Interest Group
10:00–11:00 a.m.
Call: 1-866-285-7778
Access Code: 4636762

 25

CTSA Consortium Meeting
Administration Grants Management Taskforce
1:00–2:00 p.m.
Call: 1-866-285-7778
Access Code: 2364694

CTSA Consortium Meeting
Biostatistics/ Epidemiology/Research Design Evaluation Task Force
4:00–5:00 p.m.
Call: 1-866-285-7778
Access Code: 2467828

 

 26

CTSA Consortium Meeting
Public Private Partnerships
3:30–5:00 p.m.

NIH coordinators
Mark Scheideler
Lili Portilla

 

 27

CTSA Consortium Meeting
Biostatistics/ Epidemiology/ Research Design
3:00–4:00 p.m.
Web Participation
Call: 1-866-485-7855
Access Code: 853014

NIH coordinators
Iris Obrams
Dennis Dixon
Paul Wakim

CTSA Consortium Meeting
Communications Communication Systems and Information Management Taskforce
3:00–4:00 p.m.
Call: 1-866-285-7778
Access Code: 6864228

 

 28

CTSA Consortium Meeting
Regulatory Knowledge
2:00–3:00 p.m.

Democracy 1, Room 1037
Web Participation
Call: 1-866-244-8528
Access Code: 946313

NIH coordinator
Jody Sachs

CTSA Consortium Meeting
Community Engagement
12:00–1:00 p.m.

NIH coordinators
Betty Tai
Donna Jo McCloskey

CTSA Consortium Meeting
Informatics
Operations Committee
12:00–1:00 p.m.
Call: 1-866-285-7778
Access Code: 4636762

 31

CTSA Consortium Meeting
Informatics
User Needs Interest Group
10:00–11:00 a.m.
Call: 1-866-285-7778
Access Code: 4636762

 1

CTSA Consortium Meeting
Administration
1:00–2:00 p.m.
Call: 1-866-285-7778
Access Code: 2364694

NIH coordinators
Elaine Collier
Kameha Kidd
Iris Obrams

 2

CTSA Consortium Meeting

Communications Operations Committee
11:00 a.m.–12:00 p.m.
Call: 1-866-285-7778
Access Code: 6864228

 

 3

CTSA Consortium Meeting

Translational
2:00–3:00 p.m.
Bethesda, Democracy 1, Conference Room 987
Web Participation

Call: 1-866-519-2804
Access Code: 704005

NIH coordinator
Doug Sheeley

 4

CTSA Consortium Meeting
Informatics Directors and Project Group Leads
1:00–2:00 p.m.
Call: 1-866-285-7778
Access Code: 4636762
* Please note that the meetings and events listed in this newsletter are provided for your information. If you wish to participate, please contact the NIH coordinator.
 
Updated Information on CTSAweb.org

CTSAweb.org was developed to ensure access to CTSA resources, enhance communication, and encourage sharing. The site continues to evolve with the CTSA in promoting this new direction of clinical and translational science.

Additional features and updates:

  • New–View Institutional CTSA Events on the Events page
  • New–View National and Local Media coverage of the CTSAs on the CTSAs in the News page
  • Link– to updated NIH CTSA information through the NIH CTSA Information page
  • Get to the CTSA Wiki from CTSAweb.org! Click on the "Consortium Login" link from the top banner on the CTSA Home Page to go directly to the CTSA Wiki.
  • Download CTSA Fact Sheets highlighting the 2006 Grantees and 2007 Grantees from the Communications Toolkit page
  • View upcoming meetings and access previous meeting information through the Calendar
  • View CTSA Committee Representatives from each grantee institution
  • View publicly available resources that promote clinical and translational research on the Resources for Researchers page

Access archived CTSA e-Newsletters on the CTSAweb.org CTSAs in the News page.


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We hope you find this newsletter helpful and informative. If you have any questions or comments, please direct them to Kameha Kidd, Office of Science Policy and Public Liaison, NCRR.