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Baylor College of Medicine–Children (Houston)

Baylor College of Medicine–Children

General Clinical Research Center
Texas Children's Hospital
Mail Station I-3420
6621 Fannin Street
Houston, TX 77030

Web site: http://www.bcm.edu/pediatrics/index.cfm external link, opens in new window

Grant No. M01 RR00188

Special Assays, Services, or Tests

Metabolic balances
Neurodevelopmental assessments

Special Resources, Instruments, or Services

Dual-energy X-ray absorptiometry
GC/IR/MS
GC/MS
Gene vector core laboratory
Indirect calorimetry (hood and room)
Instruments and skills for evaluation of health care outcomes and health services delivery
Total-body electrical conductivity analyzer
Whole-body ⁴⁰K counter

Major Areas of Investigation

Allergy and Immunology: AIDS Clinical Trials Group: vertical transmission of AIDS; heart and lung complications; audiologic function; oral manifestations; severe combined immunodeficiency disorders; asthma.

Critical Care: Long-term outcomes of pediatric intensive care unit (PICU) patients; work of breathing and mechanically ventilated patients: gastric intramucosal pH and predictor of cardiac output in children on mechanical ventilation; protein intake and nitrogen balance in PICU patients on total parenteral nutrition.

Endocrinology: Metabolic role of hormones in pubertal growth; effects of hormones on calcium metabolism; studies in clinical disorders of hypopituitarism, Turner's syndrome, diabetes mellitus.

Gene Therapy: Hepatic gene transplantation; gene therapy for pediatric AIDS; urea cycle disorders gene therapy; thymidine kinase gene therapy in children with brain tumors.

Genetic Diseases: Urea cycle disorders; contiguous gene deletion syndromes (Smith-Magenis, Prader-Willi, DiGeorge, Angelmann, Potocki-Shaffer, and Williams syndromes, and Fabry disease).

Infectious Diseases: Maternal-infant cytomegalovirus; Norwalk virus vaccine.

Neonatal Nutrition: Gluconeogenesis in very-low-birthweight infants; Ca and P metabolism and skeletal mineralization; early feeding strategies and development in low-birthweight infants; sulfur amino acid metabolism in low-birthweight infants; quality of energy intake in low-birthweight infants; essential fatty acid metabolism in very-low-birthweight and term infants.

Neurology: Hereditary ataxias; Rett syndrome.

Oncology: Pharmacokinetics of chemotherapy in CNS tumors.

Surgery: Islet cell transplantation.

Contact Information

For information about this GCRC and how to access its resources, please contact:

Administrative Manager
Angela Doggett, B.B.A.
832-826-1079; Fax: 832-825-1061
E-mail: doggett@bcm.edu

Program Director
Dennis M. Bier, M.D.
713-798-7022; Fax: 713-798-7046
E-mail: dbier@bcm.tmc.edu

Principal Investigator
Ralph D. Feigin, M.D.
713-798-4433; Fax: 713-798-8811
E-mail: rfeigin@bcm.tmc.edu

Associate Program Director
Ann R. Stark, M.D.
832-826-1380; Fax: 832-825-2799
E-mail: arstark@bcm.tmc.edu

Associate Program Director
Susan Blaney, M.D.
832-822-1482; Fax: 832-825-4299
E-mail: sblaney@bcm.tmc.edu

Research Subject Advocate
Lisa R. Bomgaars, M.D.
832-824-4629; Fax: 832-825-4039
E-mail: bomgaars@bcm.tmc.edu

GCRC Advisory Committee Chairperson
David G. Poplack, M.D.
832-822-4556; Fax: 832-825-4299
E-mail: dpoplack@bcm.tmc.edu

Nurse Manager, Pediatric Unit
Kathy Green, R.N., M.B.A.
832-826-5152; Fax: 832-825-1061
E-mail: kogreen@texaschildrenshospital.org

Core Laboratory Director
Adrian Gee, Ph.D.
832-824-4214; Fax: 832-825-4668
E-mail: agee@bcm.tmc.edu

Nutritionist
Janice Stuff, Ph.D., R.D.
713-798-7066; Fax: 713-798-7098
E-mail: jstuff@bcm.tmc.edu

Nutritionist
Ann McMeans, M.S., R.D.
832-824-2584; Fax: 832-824-1393
E-mail: amcmeans@bcm.tmc.edu

Biostatistician
Claudia Kozinetz, Ph.D., M.P.H.
832-824-3730; Fax: 832-825-3697
E-mail: kozinetz@bcm.tmc.edu

Biostatistician
E. O'Brian Smith, Ph.D.
713-798-7058; Fax: 713-798-7046
E-mail: esmith@bcm.tmc.edu