Technology for Structural Biology
Twelve Biomedical Technology Research Resources (BTRRs) are supported in the broad area of Structural Biology to develop technologies for studying the structures of biomolecules in the size range of peptides to cells using nuclear magnetic resonance (NMR), synchrotron radiation and multiple types of microscopy. A combined goal of Structural Biology and Systems Biology areas is to understand the functions and mechanisms of important biological molecules in their various forms and in the different places they show up in the cell throughout the cell cycle.
Research Resource
• |
BioCARS: A Synchrotron Structural Biology Resource
synchrotron
center for macromolecular
crystallography
|
Principal Investigator
Keith Moffat, Ph.D. |
• |
Biophysics Collaborative Access Team
x-ray scattering usign synchrotron radiation to study macromolecular structure
|
Principal Investigator
Thomas Irving, Ph.D. |
• |
Macromolecular Crystallography at the National Synchrotron Light Source
synchrotron
center for macromolecular
crystallography
|
Principal Investigator
Robert M. Sweet, Ph.D. |
• |
Macromolecular Diffraction Biotechnology Resource
isynchrotron
center for macromolecular
crystallography |
Principal Investigator
Richard A. Cerione, Ph.D. |
• |
National Biomedical Center for Advanced ESR Technology
electron spin resonance technology
|
Principal Investigator
Jack H. Freed, Ph.D. |
• |
National Magnetic Resonance Facility at Madison
nuclear magnetic resonance spectroscopy
|
Principal Investigator
John L. Markley, Ph.D. |
• |
National Resource for Automated Molecular Microscopy
electron microscopy at the molecular level |
Principal Investigator
Bridget Carragher |
• |
Synchrotron Radiation Structural Biology Resource
synchrotron center for macromolecular crystallography |
Principal Investigator
Keith O. Hodgson, Ph.D. |
• |
Three-Dimensional Electron Microscopy of Macromolecules
CryoEM at subnanometer resolution |
Principal Investigator
Wah Chiu, Ph.D. |
• |
Three-Dimensional Fine Structure of Cells and Tissues
electron microscopy at the cellular level |
Principal Investigator
Andreas Hoenger, Ph.D. |
• |
Undulator Resource for Structural Biology
synchrotron
center for macromolecular crystallography |
Principal Investigator
Steven E. Ealick, Ph.D. |
• |
Visualization of Biological Complexity Resource
electron microscopy at the molecular level |
Principal Investigator
Joachim Frank, Ph.D. |
Contact Information
For further information about NCRR support for Technology for Structural Biology resources, contact:
Amy L. Swain, Ph.D.
Division of Biomedical Technology
National Center for Research Resources
National Institutes of Health
One Democracy Plaza, Room 962
6701 Democracy Boulevard, MSC 4874
Bethesda, Maryland 20892-4874 (20817 for express mail)
Telephone: 301-435-0755
Fax: 301-480-3659
E-mail: SwainA@mail.nih.gov
